With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.42831-50-5,5-Methylisoxazole-4-carboxylic acid,as a common compound, the synthetic route is as follows.
Thionyl chloride (4.3 ml, 39.5 mmol) was added dropwise to 5-methylisoxazole-4-carboxylic acid (0.44 g, 3.4 mmol) at 26C. The mixture was heated at 89C for 1 hr and allowed to cool. Excess thionyl chloride was evaporated under reduced pressure to give an acid chloride as a brown oil, which was used in the next reaction.
42831-50-5, As the paragraph descriping shows that 42831-50-5 is playing an increasingly important role.
Reference£º
Patent; The New Industry Research Organization; EP1627873; (2006); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem