Category: 96530-57-3

Difunctionalization of the Isocyano Group: Atom-Economic Synthesis of Pyrimidinediones was written by Lang, Jian;Wei, Ye. And the article was included in Synlett in 2019.Computed Properties of C6H7NO4 The following contents are mentioned in the article:

The exploration of synthetic methods involving the formation of new chem. bonds at both the nitrogen and carbons atoms of the isocyano group would largely enrich the structural diversity of compounds Herein, we disclosed a silver-catalyzed difunctionalization of the isocyano group with cyclic oximes. This method can generate a great array of structurally novel and interesting pyrimidinediones and features excellent atom economy, good functional group compatibility, and amenability to late-stage modifications. This study involved multiple reactions and reactants, such as Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3Computed Properties of C6H7NO4).

Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3) belongs to isoxazole derivatives. Isoxazoles are aromatic heterocycles containing an N–O bond. The weakness of this bond allows the ring opening of these heterocycles under reductive conditions. As with isoxazolines, isoxazoles may be cleaved using low-valent titanium obtained from the Kulinkovich reaction.This procedure affords enaminoketones from 2,4-substituted isoxazoles.Computed Properties of C6H7NO4

Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem

Unusual Approach to Branched 3-Alkynylamides and to 1,5-Dihydropyrrol-2-ones was written by Dias-Jurberg, Igor;Gagosz, Fabien;Zard, Samir Z.. And the article was included in Organic Letters in 2010.Name: Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate The following contents are mentioned in the article:

Rare carboxamide branched alkynes, such as I, can be readily obtained by reaction of the electrophilic 4-alkylidene isoxazolinones, e.g. II, with isocyanides, e.g. t-BuNC, followed by nitrosative cleavage of the heterocyclic ring. N-Iodosuccinimide-induced ring closure of these alkynamides in the presence of a nucleophile results in the formation of new iodopyrrolinones, such as III (R = H, Me, H₂C:CHCH₂). This study involved multiple reactions and reactants, such as Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3Name: Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate).

Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3) belongs to isoxazole derivatives. An isoxazolyl group is found in many beta-lactamase-resistant antibiotics, such as cloxacillin, dicloxacillin and flucloxacillin. Isoxazole can be synthesised via a variety of methods. Examples include via the reaction of hydroxylamine with 1,3-diketones or derivatives of propiolic acid.Name: Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate

Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem

Atom-Economic Silver-Catalyzed Difunctionalization of the Isocyano Group with Cyclic Oximes: Towards Pyrimidinediones was written by Liang, Hong-Wen;Yang, Zhen;Jiang, Kun;Ye, Ying;Wei, Ye. And the article was included in Angewandte Chemie, International Edition in 2018.Related Products of 96530-57-3 The following contents are mentioned in the article:

An unprecedented silver-catalyzed difunctionalization of the isocyano group with cyclic oximes is described. This method allows efficient and atom-economic assembly of a vast array of structurally novel and interesting pyrimidinediones, and tolerates a range of functionalities. The resulting products can be easily converted into some useful compounds Furthermore, the method can also be applied for the late-stage modification of a few biol. active mols. This study involved multiple reactions and reactants, such as Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3Related Products of 96530-57-3).

Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3) belongs to isoxazole derivatives.Synthetically, isoxazoles serve as valuable precursors for the construction of diverse molecules, including many natural products. Isoxazoles are potent isosteres of pyridine and have been found to inhibit voltage-gated sodium channels for pain control, for the construction of tetracycline antibiotic derivatives, and as a therapeutic agent for depression.Related Products of 96530-57-3

Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem

A new synthesis of 5,7-dicarboxy-2,1-benzisoxazolin-3-one was written by Kim, C. K.;Krasavage, B. A.;Maggiulli, C. A.. And the article was included in Journal of Heterocyclic Chemistry in 1985.Application of 96530-57-3 The following contents are mentioned in the article:

Condensation of isoxazolinone I and Me₂NCH:C(CHO)CO₂Et gave benzisoxazolinone II (R = Me, R¹ = Et). Simple hydrolysis of the latter compound afforded the title compound (II, R = R¹ = H). This study involved multiple reactions and reactants, such as Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3Application of 96530-57-3).

Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3) belongs to isoxazole derivatives.Synthetically, isoxazoles serve as valuable precursors for the construction of diverse molecules, including many natural products. The electrophilic cyclization of various 2-alkynone O-methyl oximes with a wide range of substrates such as ICl, I2, Br2, PhSeBr, etc. provides a variety of 3,4,5-trisubstituted isoxazoles in good to excellent yields.Application of 96530-57-3

Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem