Atom-Economic Silver-Catalyzed Difunctionalization of the Isocyano Group with Cyclic Oximes: Towards Pyrimidinediones was written by Liang, Hong-Wen;Yang, Zhen;Jiang, Kun;Ye, Ying;Wei, Ye. And the article was included in Angewandte Chemie, International Edition in 2018.Related Products of 96530-57-3 The following contents are mentioned in the article:
An unprecedented silver-catalyzed difunctionalization of the isocyano group with cyclic oximes is described. This method allows efficient and atom-economic assembly of a vast array of structurally novel and interesting pyrimidinediones, and tolerates a range of functionalities. The resulting products can be easily converted into some useful compounds Furthermore, the method can also be applied for the late-stage modification of a few biol. active mols. This study involved multiple reactions and reactants, such as Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3Related Products of 96530-57-3).
Methyl 2-(5-oxo-4,5-dihydroisoxazol-3-yl)acetate (cas: 96530-57-3) belongs to isoxazole derivatives.Synthetically, isoxazoles serve as valuable precursors for the construction of diverse molecules, including many natural products. Isoxazoles are potent isosteres of pyridine and have been found to inhibit voltage-gated sodium channels for pain control, for the construction of tetracycline antibiotic derivatives, and as a therapeutic agent for depression.Related Products of 96530-57-3
Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem