100499-66-9, 5-Methylisoxazol-4-amine hydrochloride is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(A-70) According to the method of the reference(J. Org. Chem. 1987, 52, p2714), (5-methylisoxazole-4-yl)amine hydrochloride(16.15g, 120mmol) was reacted with 4-fluorophenylacetyl chloride(20.8g, 120mmol) in the presence of triethylamine to give 2-(4-fluorophenyl)-N-(5-methylisoxazole-4-yl)acetamide(22.55g, yield:80%). NMR(CDCl3)delta: 2.28(3H, s), 3.69(3H, s), 6.71(1H, brs), 7.06-7.20(2H, m), 7.26-7.32(2H, m), 8.46(1H, s)., 100499-66-9
As the paragraph descriping shows that 100499-66-9 is playing an increasingly important role.
Reference£º
Patent; SHIONOGI & CO., LTD.; EP1422218; (2004); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem