Zhu, Shuai’s team published research in Green Chemistry in 19 | CAS: 1076-59-1

Green Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H10O3S, Application of 3-Phenylisoxazol-5(2H)-one.

Zhu, Shuai published the artcileConstruction of the tetrahydroquinoline spiro skeleton via cascade [1,5]-hydride transfer-involved C(sp3)-H functionalization “on water”, Application of 3-Phenylisoxazol-5(2H)-one, the publication is Green Chemistry (2017), 19(23), 5653-5658, database is CAplus.

The pharmaceutically important tetrahydroquinoline spiro compounds, e.g., I were efficiently constructed via cascade SNAr/Knoevenagel condensation/[1,5]-hydride transfer/cyclization on water, featuring high atom-economy and step-economy. This water-based redox-neutral C(sp3)-H functionalization rendered a 4-step cascade reaction successful without resorting to any catalysts.

Green Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H10O3S, Application of 3-Phenylisoxazol-5(2H)-one.

Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem