Zhou, Yu-jing published the artcileEffect of preemptive analgesia with parecoxib sodium on pain after laparoscope in gynecology department, Product Details of C19H17N2NaO4S, the publication is Hainan Yixueyuan Xuebao (2015), 21(10), 1422-1424, database is CAplus.
Objective: To observe the effect of preemptive analgesia with parecoxib sodium on pain after laparoscope in gynecol. department. Methods: A total of 100 cases with surgery under laparosocope, at stage ASA I-II, admitted from Jan. 2013 to Feb. 2014 were selected. They ere randomly divided into observation group and control group. Patients in observation group were treated with i.v. injection of parecoxib sodium 40 mg 30 min before surgery, and with i.v. injection of fentany1 citrate 1.0 μg/kg 30 min before the end of surgery. Patients in control group were treated with i.v. injection of parecoxib sodium 40 mg and fentany1 citrate 1.0 μg/kg 30 min before the end of surgery. The analgesia and sedative effect at 4, 8, 12 h after surgery were observed The addnl. dosage of fentany1 and the incidence of side effect were also observed Results: Analgesia score VAS at every time point and total dosage of fentanyl were significantly lower in observation group (P<0.05). There was no significant difference in Ramsay sedative score and incidence of side effect between two groups (P>0.05). Conclusions: Preemptive analgesia with parecoxib sodium can reduce the dosage, and is of exact analgesia effect. It is worthy clin. application.
Hainan Yixueyuan Xuebao published new progress about 198470-85-8. 198470-85-8 belongs to isoxazole, auxiliary class Immunology/Inflammation,COX, name is Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, and the molecular formula is C13H26N2, Product Details of C19H17N2NaO4S.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem