Brzezinski, B.; Zundel, G. published an article about the compound: 1-Piperidineacetic Acid( cas:3235-67-4,SMILESS:OC(=O)CN1CCCCC1 ).Application In Synthesis of 1-Piperidineacetic Acid. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:3235-67-4) through the article.
IR spectra were plotted for (C5H10N)(CH2)nCOOH (n = 1-4) in CDCl3 solutions From the carboxylic bands, information is obtained on whether the proton is present at the carboxylic group or at the N atom. Furthermore, an IR continuum indicates the presence of easily-polarizable H bonds. With 1-piperidineacetic acid, the proton is found at the N atom. Intermol. asym. O-…H+N H bonds are formed, which are not easily polarizable. When n = 2-4, intramol. OH…N ⇄ O-…H+N bonds are found with the proton distributed between the O and N atoms. A double min. energy surface is present in these bonds. A strong IR continuum indicates that these H bonds are easily polarizable. With increasing concentration, the weight of the polar proton boundary structure O-…H+N increases due to interaction effects between these H bonds. These interaction effects do not occur when n = 4, as they are hindered by the hydrocarbon skeleton. In the case of intermol. OH…N ⇄ O-…H+N bonds, the IR continuums show structures in the 3200-1800 cm-1 region. These structures are not observed with the intramol. bonds, as these are shorter. Addition of water causes dissociation of the intramol. OH…N ⇄ O-…H+N H bonds.
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem