Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Trimethylphosphineoxide, is researched, Molecular C3H9OP, CAS is 676-96-0, about 1H-31P HETCOR NMR elucidates the nature of acid sites in zeolite HZSM-5 probed with trimethylphosphine oxide.Safety of Trimethylphosphineoxide.
Two-dimensional 1H-31P heteronuclear correlation NMR of trimethylphosphine oxide (TMPO) adsorbed in zeolites, in tandem with DFT calculations, challenges previous one-dimensional 31P NMR assignments, enabling the unambiguous discrimination of Bronsted and Lewis acid sites, extending the understanding of TMPO:Bronsted complexes formed with distinct stoichiometries at the HZSM-5 zeolite surface, and the proton-transfer mechanism.
In addition to the literature in the link below, there is a lot of literature about this compound(Trimethylphosphineoxide)Safety of Trimethylphosphineoxide, illustrating the importance and wide applicability of this compound(676-96-0).
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem