Poomathi, Nataraj published the artcileReaction of isatins with 6-amino uracils and isoxazoles: isatin ring-opening vs. annulations and regioselective synthesis of isoxazole fused quinoline scaffolds in water, Name: 3-Phenylisoxazol-5(2H)-one, the publication is Green Chemistry (2015), 17(6), 3362-3372, database is CAplus.
A green and efficient straightforward approach for the regioselective synthesis of novel 6-amino-5-(3-phenylisoxazolo[5,4-b]quinolin-4-yl)pyrimidine-2,4(1H,3H)-diones and 3-methyl-1-phenyl-4-(3-phenylisoxazolo[5,4-b]quinolin-4-yl)-1H-pyrazol-5-amines via the cleavage of the isatin C-N bond followed by a ring expansion reaction in a one-pot manner has been established using environmentally benevolent p-toluene sulfonic acid as a catalyst. An exciting feature of this article is the reaction mechanism that depends on the nature of the group attached to the isatin ring nitrogen atom. The main advantages of this protocol include a short reaction time, an excellent yield, easy work-up, practical simplicity, high regioselectivity and the absence of extraction and chromatog. purification steps.
Green Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Name: 3-Phenylisoxazol-5(2H)-one.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem