Kristofikova, Dominika published the artcileMechanochemically Activated Asymmetric Organocatalytic Domino Mannich Reaction-Fluorination, HPLC of Formula: 1076-59-1, the publication is ACS Sustainable Chemistry & Engineering (2020), 8(38), 14417-14424, database is CAplus.
Mechanochem. activation effectively mediated asym. organocatalytic domino Mannich addition followed by diastereoselective fluorination. The Mannich reactions of pyrazolone and to a lesser extent of isoxazolones were effective under solvent-free ball-milling conditions. This reaction in combination with chiral squaramide catalyst provided corresponding products in high yields and enantiomeric purities up to 99:1 e.r. and as a single diastereomer. DFT calculations revealed reasons for high diastereoselectivity. Mechanochem. activation shortens reaction time and increase mass intensity of the stereoselective organocatalytic Mannich reaction-fluorination that afford chiral heterocyclic compounds
ACS Sustainable Chemistry & Engineering published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, HPLC of Formula: 1076-59-1.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem