Qiu, Tao; Zhao, Hongxu; Lu, Xinyu published an article about the compound: 2-Chloropyridine 1-oxide( cas:2402-95-1,SMILESS:ClC1=CC=CC=[N+]1[O-] ).Application In Synthesis of 2-Chloropyridine 1-oxide. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:2402-95-1) through the article.
Phosphotungstic acid immobilized on silicon dioxide is prepared as catalyst. 2-Chloropyridine-N-oxide is synthesized from 2-chloropyridine, H2O2 and catalyst. By single factor experiment, effects of mass fraction of phosphotungstic acid, catalyst dosage, molar ratio of reactants, reaction temperature and reaction time on oxidation is studied. Through repeat examinations, the optimal reaction conditions is mass fraction of phosphotungstic acid 30%, mass of catalyst 3.3%; n(2-chloropyridine):n(H2O2)=1:6.0; reaction temperature 80°C and reaction time 30 h. The optimal yield is 89.8%.
After consulting a lot of data, we found that this compound(2402-95-1)Application In Synthesis of 2-Chloropyridine 1-oxide can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem