31329-64-3, 3,5-Dimethylisoxazol-4-amine is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 1 4-Difluoromethoxy-2-ethylbenzooxazole-7-carboxylic acid (3,5-dimethylisoxazole-4-yl)-amide Oxalyl chloride (0.2 ml) was added to a suspension of 4-difluoromethoxy-2-(piperidin-1-yl)-benzooxazole-7-carboxylic acid (0.3 g) in dichloromethane (20 ml) at room temperature under an atmosphere of nitrogen. Three drops of N,N-dimethylformamide were added, and the mixture stirred for 18 hours. The solvent was removed in vacuo and the residue dissolved in dichloromethane (20 ml). The resulting solution was added to a mixture of 3,5-dimethylisoxazol-4-ylamine (0.16 g) and triethylamine (0.2 ml) in dichloromethane (20 ml) at room temperature under an atmosphere of nitrogen. The mixture was stirred for 2 hours, then washed with aqueous sodium bicarbonate (2*20 ml) and water (20 ml). The organics were dried over magnesium sulphate, filtered and the solvent removed in vacuo. Purification by column chromatography on silica eluding with 50% ethyl acetate in heptane afforded the title compound as a white solid (0.29 g). TLC Rf 0.65 (ethyl acetate). Mass spectrum m/z 350 (M-1), 31329-64-3
As the paragraph descriping shows that 31329-64-3 is playing an increasingly important role.
Reference£º
Patent; Darwin Discovery, Ltd.; US6403791; (2002); B1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem