Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 14248-66-9, is researched, Molecular C7H8N2O3, about Potentiometric studies of acid-base interactions in substituted 4-nitropyridine N-oxide systems, the main research direction is nitropyridine oxide derivative acid base equilibrium constant polar solvent.COA of Formula: C7H8N2O3.
(Acid + base) equilibrium constants, involving the acidity (pKACa) and cationic homoconjugation constants (in the form of lg KANBHB+), have been determined by the potentiometric method in 13 systems formed by substituted 4-nitropyridine N-oxides in the polar aprotic solvent, acetone (AC). The derivatives covered a wide range of proton-acceptor properties and inherent diversified tendencies towards formation of hydrogen-bonded cations. In addition, the constant values (expressed as pKANa and lg KANBHB+) for two of the systems studied, N-oxides of 2-methylamino- and 2-ethylamino-4-nitropyridine, were determined in acetonitrile (AN). The acidity constants in the non-aqueous media studied have been found to change in line with their substituent effects and the sequence of acidity changes in water. The values of the cationic homoconjugation constants increased with increasing basicity of the N-oxides and decreased with increasing solvent basicity.
From this literature《Potentiometric studies of acid-base interactions in substituted 4-nitropyridine N-oxide systems》,we know some information about this compound(14248-66-9)COA of Formula: C7H8N2O3, but this is not all information, there are many literatures related to this compound(14248-66-9).
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem