Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 17153-20-7, Name is 3-Methylisoxazole-4-carboxylic acid, molecular formula is C5H5NO3, belongs to Isoxazoles compound, is a common compound. In a patnet, author is Zhao Jiangyu, once mentioned the new application about 17153-20-7, Recommanded Product: 3-Methylisoxazole-4-carboxylic acid.
Synthesis of Novel Isoxazole Contained Rupestonic Acid Derivatives and in vitro Inhibitory Activity against Influenza Viruses A and B
To improve biological activity of rupestonic acid, six rupestonic acid amide derivatives containing isoxazole were synthesized in the presence of DCC, HOBt/DMAP using the rupestonic acid and 3-aryl-5-isoxazole-methylamine as the starting materials. The synthesized compounds 3a similar to 3f were confirmed by the methods of H-1 NMR, C-13 NMR, IR, ESI-MS techniques and preliminarily assayed in vitro against influenza viruses A and B. The results showed that compound 3c showed better activity against both influenza viruses A (H3N2) and B, and compounds 3c and 3e had the higher inhibition against influenza B virus than the parent compound 1.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 17153-20-7. The above is the message from the blog manager. Recommanded Product: 3-Methylisoxazole-4-carboxylic acid.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem