Awesome and Easy Science Experiments about 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid

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In an article, published in an article,authors is Baudin, Jean-Bernard, once mentioned the application of 33282-15-4, Name is 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid,molecular formula is C10H7NO4, is a conventional compound. this article was the specific content is as follows. 33282-15-4

A NEW PREPARATION OF N-ARYL-1-ALKYNESULPHENAMIDES AND THEIR THERMAL REARRANGEMENTS INTO INDOLINE-2-THIONES

Reaction of 1-alkynyl-lithio derivatives with N,N-dialkylaminosulphenyl chlorides 3a,b affords the N,N-dialkyl-1-alkynesulphenamides 4.When treated with stoichiometric amounts of a substituted benzenamine and methanesulfonic (or trifluoroacetic) acid, the sulphenamides 4, are converted into N-aryl-1-alkynesulphenamides 6-20.On heating in benzene, many of these sulphenamides 6-20 undergo <3.3>-sigmatropic rearrangements followed by cyclisation of the intermediate thioketenes yielding the substituted indoline-2-thiones 21-30.

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Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem