Kimura, Katsuhiko; Nagaoka, Masao; Ohgiya, Shozaburo published the article 《Difference spectra of P-450 in rat liver microsomes induced by piperidine N-derivatives and the spectral dissociation constant of each derivative》. Keywords: microsome cytochrome P 450 piperidine.They researched the compound: 1-Piperidineacetic Acid( cas:3235-67-4 ).Quality Control of 1-Piperidineacetic Acid. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:3235-67-4) here.
Piperidinoacetic acid [3235-67-4], N-cinnamylpiperidine [70552-70-4] and 3-piperidino-1-phenyl-1-propanone [73-63-2] caused type I spectral changes of cytochrome P-450 [9035-51-2] in reaction with the rat liver microsomes, whereas N-methylpiperidine (I) [626-67-5] caused type II spectral change. 2-Piperidinoethanol [3040-44-6] caused a modified type II spectral change. The apparent dissociation constants calculated from spectral changes for varying concentrations of the above compounds were in close correlation with the rates of N-C cleavage of those compounds by the microsomes.
There are many compounds similar to this compound(3235-67-4)Quality Control of 1-Piperidineacetic Acid. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem