So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Raghoottama, P. S.; Soundararajan, S.; Ramakrishna, J. researched the compound: 2-Chloropyridine 1-oxide( cas:2402-95-1 ).Electric Literature of C5H4ClNO.They published the article 《Chlorine-35 nuclear quadrupole resonance study of molecular torsional motion in some chloropyridine-N-oxides and chloroquinoline-N-oxides》 about this compound( cas:2402-95-1 ) in Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics. Keywords: NQR chlorine chloropyridine oxide; torsional dynamics chloropyridine oxide. We’ll tell you more about this compound (cas:2402-95-1).
Chlorine has been substituted at the 2- and 4-positions in the pyridine and quinoline rings of the corresponding N-oxides and 35Cl NQR spectra have been studied in the temperature range 77-300 K. The change in the NQR frequencies in N-oxides as compared to their parent compds are interpreted in terms of the conjugative effect and the inductive effect of the N+-O- group. The neg. temperature coefficients of the resonance frequencies in chloropyridine N-oxides have been analyzed using the Bayer, Kushida and Brown equations. The calculated torsional frequencies, which are in the range 52-78 cm-1, are only slightly temperature dependent.
In addition to the literature in the link below, there is a lot of literature about this compound(2-Chloropyridine 1-oxide)Electric Literature of C5H4ClNO, illustrating the importance and wide applicability of this compound(2402-95-1).
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem