Application of 3235-67-4. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-Piperidineacetic Acid, is researched, Molecular C7H13NO2, CAS is 3235-67-4, about Search for anticholinergic compounds. XLV. Structure and pharmacological activity of some esters of alkylamino acids: piperidino-, morpholino-, dicyclohexylamino-, phenylcyclohexylamino-, diphenylamino-, benzylphenylamino-, and benzylcyclohexylaminoacetic acids. Author is Wolinski, Jerzy; Prokopienko, Grazyna.
The anticholinergic activity of a number of esters of acetic and aminoacetic acid derivatives was assessed as a function of the Schild index value. The highest activity was observed when piperidine was part of the alc. moiety and the acid moiety contained a branched substituent. With branched substituents in both the acid and the alc. moiety, activity decreased markedly. Aminoacetate esters were more active than the analogous acetate esters, the presence of 2 -O-C-C-N- groups in the mol. apparently being the reason behind this observation. 2-(1-Piperidinyl)ethyl diphenylaminoacetate [102964-41-0] was more active than pipethanate [4546-39-8].
In addition to the literature in the link below, there is a lot of literature about this compound(1-Piperidineacetic Acid)Application of 3235-67-4, illustrating the importance and wide applicability of this compound(3235-67-4).
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem