Wannenmacher, Nick published the artcileCatalytic Asymmetric Chlorination of Isoxazolinones, HPLC of Formula: 1076-59-1, the publication is European Journal of Organic Chemistry (2022), 2022(9), e202200030, database is CAplus.
The first catalytic asym. chlorination of isoxazolinones I (R1 = Me, Ph, 4-chlorophenyl, 4-methoxyphenyl; R 2 = Me, Bn, naphthalen-2-yl, etc.), a synthetically and biol. interesting class of heterocycles II, which can be considered as precursors for β-aminoacids was reported. The title reaction was catalyzed with high enantioselectivity by a planar chiral ferrocene based palladacycle III in high to excellent yields. It is showcased that the products are valuable for post-synthetic transformations. An SN2 reaction proceeded with smooth inversion of the absolute configuration. The substitution product II (R1 = Ph, R2 = Bn) could then be transformed into an α-azido β-aminoacid derivative IV via a reductive, diastereoselective ring opening.
European Journal of Organic Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C13H16BNO5, HPLC of Formula: 1076-59-1.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem