Top Picks: new discover of 3,5-Dimethyl-4-nitroisoxazole

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1123-49-5

Electric Literature of 1123-49-5, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.1123-49-5, Name is 3,5-Dimethyl-4-nitroisoxazole, molecular formula is C5H6N2O3. In a article,once mentioned of 1123-49-5

A chiral-At-metal asymmetric catalyzed vinylogous Michael addition of: Ortho-methyl aromatic nitro compounds for isoxazole derivative synthesis

ortho-Alkyl aromatic nitro compounds as vinylogous nucleophiles in catalytic asymmetric synthesis have rarely been reported. Herein an asymmetric vinylogous Michael addition of 5-methyl 4-nitroisoxazoles with alpha,beta-unsaturated 2-Acyl imidazoles catalyzed by a chiral-At-metal rhodium(iii) complex has been developed. The corresponding adducts were obtained in good yields (80-96%) with excellent enantioselectivities (up to 97%). The reaction can be conducted on a gram scale with a low catalyst loading (0.25 mol%) without impacting its efficiency.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1123-49-5

Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem