Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 3235-67-4, is researched, SMILESS is OC(=O)CN1CCCCC1, Molecular C7H13NO2Journal, Yakugaku Zasshi called On the pKa, distribution into organic solvents, Km and Vmax of piperidine N-derivatives and the cleavage of their N-C linkage by liver enzyme system, Author is Kimura, Katsuhiko; Nagaoka, Masao; Agatsuma, Hitoshi; Ohgiya, Shozaburo, the main research direction is piperidine derivative liver enzyme.Related Products of 3235-67-4.
Values of pKa, Km, and Vmax, and percentage of nondissocd. type, and distribution coefficient in organic solvents were measured for N-derivatives of piperidine; N-Me- [626-67-5], N-(2-hydroxyethyl)- [3040-44-6], N-carboxymethyl- [3235-67-4], and N-cinnamyl- [70552-70-4] piperidines, 3-methyl-4-piperidinobutan-2-one (I) [42327-99-1], 1-phenyl-3-piperidinopropan-1-one [73-63-2], and 1,3-diphenyl-4-piperidinobutan-2-one [70552-69-1], and correlation between these values and N-C cleavage of these derivatives is discussed. In general, derivatives having smaller pKa and Km values and those having a larger percentage of nondissocd. type distribution coefficient, and Vmax values had a greater tendency for cleavage.
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem