Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 2402-95-1, is researched, SMILESS is ClC1=CC=CC=[N+]1[O-], Molecular C5H4ClNOJournal, Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) called [1,4] and [5,5] Thermal sigmatropic rearrangements of 2-pentadienyloxypyridine N-oxides, Author is Alker, David; Ollis, W. David; Shahriari-Zavareh, Hooshang, the main research direction is pyridine oxide pentadienyloxy preparation rearrangement; pentadienyloxypyridine oxide thermal sigmatropic rearrangement; pyridone derivative.Safety of 2-Chloropyridine 1-oxide.
2-Pentadienyloxypyridine N-oxides I (R = H, R1, R2 H, Me; R = NO2, R1 = R2 = H) are smoothly transformed on heating into N-pentadienyloxy-2-pyridones II and N-hydroxy-5-pentadienyl-2-pyridones III. These reactions are regiospecific and are believed to proceed in a concerted fashion. The [5,5) sigmatropic rearrangement I → III takes place under moderate conditions and in good yield, although it presumably involves a ten-membered cyclic transition state.
As far as I know, this compound(2402-95-1)Safety of 2-Chloropyridine 1-oxide can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem