In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis of 2-[[(4-fluoroalkoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazoles as antiulcer agents, published in 1990-10-31, which mentions a compound: 14248-66-9, mainly applied to benzimidazole fluoroalkoxypyridylmethylsulfinyl preparation antiulcer, Name: 3,5-Dimethyl-4-nitropyridine 1-oxide.
Many title compounds (I, R1 = H, F, alkoxy, CF3 or MeSO2, R2 and R4 = H or Me, R3 = CF3, C2F5, HCF2CF2 or CCl3) were synthesized and tested for antisecretory, antiulcer, and cytoprotective activities. Most of these compounds were superior to omeprazole in antisecretory and antiulcer potencies, and especially in protecting the gastric mucosa from ethanol-induced damage. AG-1749 (Iansoprazole) (I, R1 = R4 = H, R2 = Me, R3 = CF3), was selected for further development and clin. evaluation.
Although many compounds look similar to this compound(14248-66-9)Name: 3,5-Dimethyl-4-nitropyridine 1-oxide, numerous studies have shown that this compound(SMILES:O=[N+](C1=C(C)C=[N+]([O-])C=C1C)[O-]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem