Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Chloropyridine 1-oxide, is researched, Molecular C5H4ClNO, CAS is 2402-95-1, about Study on catalytic oxidation preparation of crystals of 2-mercaptopyridine N-oxide sodium.Product Details of 2402-95-1.
The title compound was prepared by oxidation of 2-chloropyridine with H2O2 in the presence of the Diels-Alder adduct of anthracene and maleic anhydride, followed by reaction with NaHS. Under optimum conditions, the overall product yield reached 63.7%.
In addition to the literature in the link below, there is a lot of literature about this compound(2-Chloropyridine 1-oxide)Product Details of 2402-95-1, illustrating the importance and wide applicability of this compound(2402-95-1).
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem