21169-71-1, Name is Isoxazole-5-carboxylic acid, belongs to isoxazole compound, is a common compound. COA of Formula: C4H3NO3In an article, once mentioned the new application about 21169-71-1.
A series of acylguanidine derivatives were prepared and investigated as inhibitors of Factor Xa (FXa). These compounds were made by guanidine acylation with carboxylic acids using carbonyl diimidazole (CDI) as the coupling reagent. Conditions for the rapid synthesis and purification of these compounds are described along with their ability to inhibit FXa. The best FXa inhibitor is 1 with a FXa IC50 of 6 nM.
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Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem