Synthetic Route of 90924-12-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.90924-12-2, Name is (3-Phenyl-5-isoxazolyl)methanol, molecular formula is C10H9NO2. In a Article，once mentioned of 90924-12-2
The propargyl alcohol on reaction with aldoxime and NaOCl in DCM gave exclusively (3-arylisoxazol-5-yl) methanol 1. The compound 1 was oxidized to an aldehyde 2 followed by reaction with aniline resulted in Schiff’s base 3. The compounds 3 were further reacted with various aldehydes having alpha-hydrogen using molecular iodine as catalyst and which yielded 5-(3-alkylquinolin-2-yl)-3- aryl isoxazole derivatives 4. All the final compounds 4 were screened against four human cancer cell lines (A549, COLO 205, MDA-MB 231 and PC-3) and among these compounds 4n showed potent cytotoxicity against all the cell lines at IC50 values of <12 muM.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 90924-12-2
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem