Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Silva, NM, once mentioned the application of 638-23-3, Name is S-(Carboxymethyl)-L-cysteine, molecular formula is C5H9NO4S, molecular weight is 179.1943, MDL number is MFCD00002614, category is Isoxazoles. Now introduce a scientific discovery about this category, Recommanded Product: S-(Carboxymethyl)-L-cysteine.
New isoxazole derivatives designed as nicotinic acetylcholine receptor ligand candidates
In this work we report the synthesis and evaluation of the analgesic properties of new isosteric heterocyclic derivatives, presenting the isoxazole nucleus, designed as nicotinic acetylcholine receptor ligand candidates, analogues to alkaloid epibatidine. Compound 2-(3-methyl-5-isoxazolyl)pyridine (3) presented the best analgesic profile of this series in hot plate test, which was partially prevented by pretreatment with nicotinic receptor antagonist mecamylamine. (C) 2002 Published by Editions scientifiques et medicales Elsevier SAS.
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Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem