Chemistry is traditionally divided into organic and inorganic chemistry. Safety of 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 33282-15-4
Design, synthesis and structure-activity relationships of novel benzoxazolone derivatives as 18 kDa translocator protein (TSPO) ligands
Selective 18 kDa translocator protein (TSPO) ligands are expected to be therapeutic agents with a wide spectrum of action on psychiatric disorders and fewer side effects. We designed novel benzoxazolone derivatives and examined the structure-activity relationship (SAR) of a series of compounds with various substituents at the amide part and C-5 position. Although a number of the synthesized compounds showed high TSPO binding affinity, these compounds had poor drug-like properties. Further optimization of pharmacokinetic properties of these compounds led to discovery of compound 74, which exhibited anxiolytic effect in the rat Vogel conflict model.
If you are interested in 33282-15-4, you can contact me at any time and look forward to more communication. Safety of 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem