19788-37-5, 4-(Chloromethyl)-3,5-dimethylisoxazole is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of the product of step 4 (0.15g, 0.255 mmol) in CH2Cl2 (4 mL), Huenig’s base (0.12 g, 0.9 mmol) and 4-chloromethyl-3,5-dimethyl-isoxazole (37 mg, 0.255 mmol) was stirred at RT for 3 days under N2. After completion, the reaction was diluted with CH2Cl2 (40 mL), washed with brine (30 mL, 3x), dried (Na2SO4), filtered and evaporated to give the product as a brown oil. Product was purified by flash silica gel chromatography, eluting with 5 % [(1:9)NH4OH-CH3OH] /95 % CH2Cl2 to give a yellow solid (1.4 g), m.p. 78-80 C; FABMS 35Cl[M+1] 624.2; HRMS 35Cl[M+1]+:cal’d for C33H40N5O3Cl3:624.2508; Found : 624.2506., 19788-37-5
19788-37-5 4-(Chloromethyl)-3,5-dimethylisoxazole 88246, aIsoxazoles compound, is more and more widely used in various fields.
Reference£º
Patent; SCHERING CORPORATION; EP937069; (2006); B1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem