Qian, Yong published the artcileActivity-Based Proteome Profiling Probes Based on Woodward’s Reagent K with Distinct Target Selectivity, Application In Synthesis of 7064-33-7, the main research area is protein profiling Woodward reagent K derivative; activity-based probes; fluorescent imaging; protein labeling; proteomics.
Woodward’s reagent K (WRK) is a reactive heterocyclic compound that has been employed in protein chem. to covalently and unspecifically label proteins at nucleophilic amino acids, notably at histidine and cysteine. The authors have developed a panel of WRK-derived activity-based probes and show that surprisingly and unexpectedly, these probes are fairly selective for a few proteins in the human proteome. The WRK-derived probes show unique reactivity towards the catalytic N-terminal proline in the macrophage migration inhibitory factor (MIF) and can be used to label and, if equipped with a fluorophore, to image MIF activities in living cells.
Angewandte Chemie, International Edition published new progress about Galectin-1 Role: ANT (Analyte), ANST (Analytical Study). 7064-33-7 belongs to class isoxazole, name is 5-(3-Bromophenyl)isoxazole, and the molecular formula is C9H6BrNO, Application In Synthesis of 7064-33-7.
Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem