Chemistry is an experimental science, COA of Formula: C5H9NO4S, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 638-23-3, Name is S-(Carboxymethyl)-L-cysteine, molecular formula is C5H9NO4S, belongs to Isoxazoles compound. In a document, author is Yong Jian-Ping.
Synthesis of novel isoxazole ring containing quinazoline derivatives and in vitro inhibitory activity against PTP alpha and PTP epsilon
7-Nitro-4-chrolo-quinazoline (4) was synthesized by two-step reactions using 4-nitro-2-aminobenezic acid and formamidine acetate as starting materials. And then, 3-(substituted-phenyl)isoxazole-5-methylamine derivatives 5a similar to 5e were synthesized by synthesizing substituted benaldehyde oxime, [3+2] dipolar cycloaddition reaction with propargyl alcohol, then acylation with methanesulfonyl chloride, substitution with NaN(3) and reduction with Zn/NH(4)Cl. Subsequently, 3-(substituted-phenyl)isoxazole-5-methylamino-4(3H)-quinazoline derivatives 6a similar to 6e were obtained by solid-grinding 5a similar to 5e and 4 under the basic Al(2)O(3) at room temperature. Their structures were confirmed by IR, HNMR and ESI-MS spectra. The compounds 6a, 6c and 6d were assayed in vitro activity against PTP alpha, PTP epsilon, and showed that the tested compounds had no notable inhibitory activity in the concentration of 20 mu g/mL.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 638-23-3. COA of Formula: C5H9NO4S.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem