In an article, author is Krstic, L, once mentioned the application of 446292-10-0, Product Details of 446292-10-0, Name is (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one, molecular formula is C14H17N3O4, molecular weight is 291.3, MDL number is MFCD11977666, category is Isoxazoles. Now introduce a scientific discovery about this category.
The preparation of an isoxazole derivative of 4-hydroxycoumarin
A method for preparation of an isoxazole derivative of 4-hydroxycoumarin, 3-phenyl-5-(4-hydroxy-3-coumarinyl)-isoxazole has been described. The reaction sequence includes addition of bromine to 3-cinnamoyl-4-hydroxycoumarin, and the subsequent treatment of the obtained dibromo derivative with 2 equivalents of sodium azide. Due to steric reasons, the azido group is introduced in the beta-position with respect to the side chain carbonyl group, so that an isoxazole ring can be formed. The total yield of the reaction was 58%.
If you are interested in 446292-10-0, you can contact me at any time and look forward to more communication. Product Details of 446292-10-0.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem