So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Deng, Nan; Jiang, Zhong-liang; Wang, Yu; Guo, Yi-ping researched the compound: 2-Chloropyridine 1-oxide( cas:2402-95-1 ).Formula: C5H4ClNO.They published the article 《Improved synthesis of zinc pyridine-2-thiol-N-oxide》 about this compound( cas:2402-95-1 ) in Jingxi Yu Zhuanyong Huaxuepin. Keywords: zinc pyridine thiol oxide preparation antibacterial. We’ll tell you more about this compound (cas:2402-95-1).
At first the raw material of title compound, 2-chloropyridine-N-oxide was synthesized using 2-chloropyridine as starting material, acetic acid and hydrogen peroxide as oxidants. Then the final zinc pyridine-2-thiol-N-oxide was obtained starting from 2-chloropyridine-N-oxide via the reactions such as thiolation, preparing sodium salt, reacting with zinc sulfate and so on. And the structure of product was characterized by H NMR and MS. Finally, the optimum reaction conditions were obtained through series experiments
Although many compounds look similar to this compound(2402-95-1)Formula: C5H4ClNO, numerous studies have shown that this compound(SMILES:ClC1=CC=CC=[N+]1[O-]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem