The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-Piperidineacetic Acid( cas:3235-67-4 ) is researched.Product Details of 3235-67-4.Zhou, Zhong-zhen; Liu, Mingxin; Lv, Leiyang; Li, Chao-Jun published the article 《Silver(I)-Catalyzed Widely Applicable Aerobic 1,2-Diol Oxidative Cleavage》 about this compound( cas:3235-67-4 ) in Angewandte Chemie, International Edition. Keywords: diol aerobic oxidative cleavage silver; carboxylic acid preparation; ketone preparation; silver oxidative cleavage catalyst; 1,2-diols; aerobic oxidative cleavage; carboxylic acids; oxidation; silver catalysis. Let’s learn more about this compound (cas:3235-67-4).
The oxidative cleavage of 1,2-diols is a fundamental organic transformation. The stoichiometric oxidants that are still predominantly used for such oxidative cleavage, such as H5IO6 , Pb(OAc)4 , and KMnO4 , generate stoichiometric hazardous waste. Herein, is described a widely applicable and highly selective silver(I)-catalyzed oxidative cleavage of 1,2-diols that consumes atm. oxygen as the sole oxidant, thus serving as a potentially greener alternative to the classical transformations.
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem