Tandem mass spectrometry study of the flash vacuum pyrolysis of some 1,2,4-triazolides was written by Maquestiau, A.;Puk, E.;Flammang, R.. And the article was included in Bulletin des Societes Chimiques Belges in 1987.Product Details of 5765-44-6 This article mentions the following:
A real-time anal. of the flash-vacuum pyrolysis products of 1,2,4-triazolides was performed by tandem mass spectrometry. Thus, 1-acyltriazoles gave 5-alkyloxazoles, in competition with formation of ketenes. This ring formation occurred by a sigmatropic shift of the acyl group from N to C, loss of N, and cyclization of the biradical intermediate. In the experiment, the researchers used many compounds, for example, 5-Methylisoxazole (cas: 5765-44-6Product Details of 5765-44-6).
5-Methylisoxazole (cas: 5765-44-6) belongs to isoxazole derivatives. Isoxazole are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter. The electrophilic cyclization of various 2-alkynone O-methyl oximes with a wide range of substrates such as ICl, I2, Br2, PhSeBr, etc. provides a variety of 3,4,5-trisubstituted isoxazoles in good to excellent yields.Product Details of 5765-44-6
Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem