Luo, Xi published the artcileAnalgesic effect of different dosage of Flurbiprofen axetil in laparoseopic cholecystectomy in comparison with other analgesic drugs, Recommanded Product: Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, the publication is Pakistan Journal of Pharmaceutical Sciences (2017), 30(5), 1895-1898, database is CAplus.
Flurbiprofen axetil is a non-selective cyclooxygenase inhibitor. It can target the aggregation with lipid micro sphere as drug carrier. and exert analgesic effect in surgical incision and inflammatory site. In laparoscopic cholecystectomy comparative study on analgesic effect of parecoxib and flurbiprofen axetil is relatively less. Therefore. this paper is mainly based on the observation of patients after resting VAS score. adverse reaction time and movement. to evaluate the analgesic effect of different drug dose of flurbiprofen and parecoxib sodium. which provides reference for clin. medication. The results show that the i.v. injection of parecoxib could provide effective analgesic effect in laparoscopic cholecystectomy. Also. compared with flurbiprofen. parccoxib shows a more significant analgesic effect.
Pakistan Journal of Pharmaceutical Sciences published new progress about 198470-85-8. 198470-85-8 belongs to isoxazole, auxiliary class Immunology/Inflammation,COX, name is Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, and the molecular formula is C19H17N2NaO4S, Recommanded Product: Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem