Kausar, Nazia’s team published research in Molecular Diversity in 21 | CAS: 1076-59-1

Kausar, Nazia published the artcileA green synthetic approach toward the synthesis of structurally diverse spirooxindole derivative libraries under catalyst-free conditions, Quality Control of 1076-59-1, the publication is Molecular Diversity (2017), 21(2), 325-337, database is CAplus and MEDLINE.

A catalyst-free green methodol. for the synthesis of pharmacol. important spirooxindole derivatives has been developed by a three-component domino reaction between isatin, various amino compounds, and 1,3-dicarbonyl or 3-phenylisoxazolone compounds in Et L-lactate medium at room temperature This new efficient synthetic method facilitated the formation of a wide range of biol. significant spirooxindole derivatives (including 17 new spirooxindoles) under very mild conditions. The cytotoxic activity of one of the isoxazole-fused spirooxindoles was evaluated in MDA-MB 468 breast cancer cell line. It was found that cell survivability decreases with increasing concentration of the selected compound in MDA-MB 468 breast cancer cells.

Molecular Diversity published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Quality Control of 1076-59-1.

Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem