Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: Boc-GABA-OH, 57294-38-9, Name is Boc-GABA-OH, SMILES is O(C(C)(C)C)C(=O)NCCCC(=O)O, belongs to Isoxazoles compound. In a document, author is Kim, HJ, introduce the new discover.
A facile synthesis of 3,4-disubstituted isoxazole derivatives by regioselective cleavage of pyrano[3,4-c]isoxazoles with boron trihalide
4,5-Dihydro-7H-pyrano[3,4-c]isoxazoles 4 were efficiently prepared by the intramolecular nitrile oxide-alkyne cycloaddition following the Michael addition of sodium alkoxide to nitroalkene. Reaction of pyrano[3,4-c]isoxazole 4 with boron trihalide resulted in regioselective benzylic C-O bond cleavage to furnish a 3,4-disubstituted isoxazole (5, 6) in high yield.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 57294-38-9. Recommanded Product: Boc-GABA-OH.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem