Gutmann, Bernhard published the artcileSynthesis of 5-Substituted 1H-Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High-Temperature Microreactor Approach, Name: 5-(4-(Trifluoromethyl)phenyl)-1H-tetrazole, the publication is Angewandte Chemie, International Edition (2010), 49(39), 7101-7105, S7101/1-S7101/12, database is CAplus and MEDLINE.
A general and scalable method for the continuous flow synthesis of 5-substituted 1H-tetrazole derivatives via addition of HN3 to organic nitriles is described. Key to this process is the in situ generation of HN3 from NaN3 and acetic acid in a microreactor coupled to an intensified high-temperature/high-pressure flow addition step to the nitrile. Under optimized conditions, tetrazole compounds are formed with quant. conversion in residence times of a few minutes, providing excellent purities and yields of isolated product.
Angewandte Chemie, International Edition published new progress about 2251-79-8. 2251-79-8 belongs to isoxazole, auxiliary class Trifluoromethyl,Fluoride,Benzene, name is 5-(4-(Trifluoromethyl)phenyl)-1H-tetrazole, and the molecular formula is C8H5F3N4, Name: 5-(4-(Trifluoromethyl)phenyl)-1H-tetrazole.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem