Griesbeck, Axel G.’s team published research in Beilstein Journal of Organic Chemistry in 7 | CAS: 1076-59-1

Beilstein Journal of Organic Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Computed Properties of 1076-59-1.

Griesbeck, Axel G. published the artcilePhotocycloaddition of aromatic and aliphatic aldehydes to isoxazoles: cycloaddition reactivity and stability studies, Computed Properties of 1076-59-1, the publication is Beilstein Journal of Organic Chemistry (2011), 127-134, database is CAplus and MEDLINE.

The first photocycloadditions of aromatic and aliphatic aldehydes to methylated isoxazoles are reported. The reactions lead solely to the exo-adducts with high regio- and diastereoselectivities. E.g., photocycloaddn of 3,4,5-trimethylisoxazole with PhCHO gave 50% exo-oxetane I. Ring methylation of the isoxazole substrates is crucial for high conversions and product stability. The 6-arylated bicyclic oxetanes, e.g. I, were characterized by X-ray structure analyses and showed the highest thermal stabilities. All oxetanes formed from isoxazoles were highly acid-sensitive and also thermally unstable. Cleavage to the original substrates is dominant and the isoxazole-derived oxetanes show type T photochromism.

Beilstein Journal of Organic Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Computed Properties of 1076-59-1.

Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem