COA of Formula: C5H5BClNO2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 6-Chloropyridine-2-boronic Acid, is researched, Molecular C5H5BClNO2, CAS is 652148-90-8, about Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates. Author is Schafer, Philipp; Palacin, Thomas; Sidera, Mireia; Fletcher, Stephen P..
Rhodium-catalyzed asym. Suzuki-Miyaura reaction of boronic acids with important partners including aryls, vinyls and heterocycles was reported to yield corresponding highly enantioenriched products. Further, it was showed that, Suzuki-Miyaura reaction of pyridine boronic acids were unsuitable, but they could be halogen-modified at the 2-position to undergo reaction and this halogen could then be removed or used to facilitate further reactions. The method was also used to synthesize isoanabasine, preclamol and niraparib an anticancer agent in several clin. trials. This method will be a useful tool in drug synthesis and discovery.
This literature about this compound(652148-90-8)COA of Formula: C5H5BClNO2has given us a lot of inspiration, and I hope that the research on this compound(6-Chloropyridine-2-boronic Acid) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem