Final Thoughts on Chemistry for 1123-49-5

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Chemistry is traditionally divided into organic and inorganic chemistry. Quality Control of 3,5-Dimethyl-4-nitroisoxazole, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 1123-49-5

Novel series of dihydro benzofuro[3,2-e]isoxazolo[4,5-b]azepin-5(5aH)-ones 6 have been synthesized from 3,5-dimethyl-4-nitroisoxazole 1. Compound 1 on treatment with salicyl aldehydes afforded the corresponding nitrostyrylisoxazoles 3, which upon reaction with ethyl bromo acetate followed by cyclization with triethylamine furnished ethyl 2,3-dihydro-3-[(3-methyl-4- nitro-5-isoxazolyl)methyl]benzofuran-2-carboxylates 5. Reductive cyclization of compounds 5 was effected with SnCl2-MeOH to give the title compounds 6. Compounds 4-6 were characterized by IR, 1H NMR, 13C NMR and Mass spectral data. The title compounds 6a-g were evaluated for their antimicrobial, anti-inflammatory, LOX-5 inhibitory, and analgesic activity. Compounds 6b and 6c exhibited significant antimicrobial activity, potent anti-inflammatory and analgesic activities as that of standard drugs.

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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem