Extracurricular laboratory:new discovery of Isoxazole

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288-14-2, Name is Isoxazole, belongs to isoxazole compound, is a common compound. Product Details of 288-14-2In an article, once mentioned the new application about 288-14-2.

A unique synthetic approach to 3-hydroxy-4-substituted picolinonitriles is achieved via gold(I)-catalyzed cyclization of 4-propargylaminoisoxazoles and subsequent N-O bond cleavage of isoxazolopyridines under mild reaction conditions in a stepwise and one-pot fashion.

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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem