Extracurricular laboratory:new discovery of 5-Methylisoxazole-4-carboxylic acid

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42831-50-5, Name is 5-Methylisoxazole-4-carboxylic acid, belongs to Isoxazoles compound, is a common compound. Product Details of 42831-50-5In an article, once mentioned the new application about 42831-50-5.

5-Substituted 4-isoxazolecarboxamides with platelet antiaggregating and other activities

The synthesis of a series of 5-substituted 4-isoxazolecarboxamides by reaction of eight 5-substituted 4-isoxazolecarbonyl chlorides with pyrrolidine, piperidine, morpholine and 4-trifluoromethylaniline is described. Some of these amides showed platelet antiaggregating activity in vitro slightly inferior to that of acetylsalicylic acid, as well weak antiinflammatory, analgesic and antipyretic activities in rats and mice.

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Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem