Chemistry is traditionally divided into organic and inorganic chemistry. category: Isoxazoles, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 33282-15-4
Current results identified 4-substituted 2-phenylaminoquinazoline compounds as novel Mer tyrosine kinase (Mer TK) inhibitors with a new scaffold. Twenty-one 2,4-disubstituted quinazolines (series 4-7) were designed, synthesized, and evaluated against Mer TK and a panel of human tumor cell lines aimed at exploring new Mer TK inhibitors as novel potential antitumor agents. A new lead, 4b, was discovered with a good balance between high potency (IC50 0.68 muM) in the Mer TK assay and antiproliferative activity against MV4-11 (GI50 8.54 muM), as well as other human tumor cell lines (GI50 < 20 muM), and a desirable druglike property profile with low log P value (2.54) and high aqueous solubility (95.6 mug/mL). Molecular modeling elucidated an expected binding mode of 4b with Mer TK and necessary interactions between them, thus supporting the hypothesis that Mer TK might be a biologic target of this kind of new active compound. If you are interested in 33282-15-4, you can contact me at any time and look forward to more communication. category: Isoxazoles
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem