Extended knowledge of Isoxazole-5-carbonyl chloride

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A GOAT inhibitors and their application in the obesity and diabetes (by machine translation)

The invention discloses a GOAT inhibitors and their application of obesity and in diabetes, Wherein: R1 , R2 , R3 , R4 Independently selected from the group of H, or CH F3 . Through the pharmacological activity experiment confirmed that the compound of the present invention 10 mum when the GOAT has better inhibition activity, can be used as inhibitors of GOAT obesity and diabetes disease in the animal model of more extensive pharmacological potency test, in order to receive the obesity and new medicine for treating diabetes. (by machine translation)

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Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem