El Kaim, Laurent published the artcileThree-component Nef-Huisgen access to 1,2,4-triazoles, Application In Synthesis of 2251-79-8, the publication is Synlett (2009), 1315-1317, database is CAplus.
A three-component triazole synthesis involving a Nef-Huisgen cascade reaction is described. After the α-addition of acyl chlorides onto isocyanides (Nef reaction), the resulting imidoyl chloride is treated with tetrazoles under suitable activation (ZnCl2). The resulting adduct is unstable and evolves according to the Huisgen reaction.
Synlett published new progress about 2251-79-8. 2251-79-8 belongs to isoxazole, auxiliary class Trifluoromethyl,Fluoride,Benzene, name is 5-(4-(Trifluoromethyl)phenyl)-1H-tetrazole, and the molecular formula is C8H5F3N4, Application In Synthesis of 2251-79-8.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem