Downstream synthetic route of 1072-67-9

As the paragraph descriping shows that 1072-67-9 is playing an increasingly important role.

1072-67-9, 5-Methylisoxazol-3-amine is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Procedure as for 14 except using 3-amino-5-methyl-isoxazole (1.5 g, 15 mmol, 1.00 equiv) and the reaction mixture was allowed to stir at RT overnight. The precipitate obtained was washed with CH2Cl2 and then vacuum dried. Pure 25b was obtained as a white crystalline solid (766 mg, 30%). m/z (ES), found 175.0221 (C6H8-ClN2O2 [M+H]+) requires 175.0196; deltaH/ppm (400 MHz, d6-DMSO):11.25 (1H, s, NH), 6.62 (1H, s, Ar-H), 4.29 (2H, s, CH2), 2.38 (3H,s, CH3).

As the paragraph descriping shows that 1072-67-9 is playing an increasingly important role.

Reference£º
Article; Reddy, Tummala R.K.; Li, Chan; Guo, Xiaoxia; Fischer, Peter M.; Dekker, Lodewijk V.; Bioorganic and Medicinal Chemistry; vol. 22; 19; (2014); p. 5378 – 5391;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem