One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, COA of Formula: C3H3NO, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 288-14-2, Name is Isoxazole, molecular formula is C3H3NO
Synthesis and antitubercular activity of isoxazole incorporated 1,2,3-triazole derivatives
Cyclization of 1-azido-4-methoxy benzene (1) with acetyl acetone in presence of sodium ethoxide gave 1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-yl)ethanone(2). Claisen-Schmidt condensation of compound 2 with different aromatic and heretocyclic aldehydes afforded triazolyl Chalcones (3a-h) which on refluxing with hydroxylamine hydrochloride in glacial acetic acid gave 4-(5-(4-substituted phenyl)isoxazol-3-yl)-1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazoles 4(a-h) in good yields. In antitubercular screening against H37RV and DUK 156, compounds 4a, 4d and 4e exhibited good activity and the results are comparable with the standard drug, Isoniazid.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. COA of Formula: C3H3NO, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 288-14-2, in my other articles.
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem