Electric Literature of 622-40-2, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 622-40-2, Name is 2-Morpholinoethanol, SMILES is OCCN1CCOCC1, belongs to Isoxazoles compound. In a article, author is Niu, Teng-fei, introduce new discover of the category.
Chemoselective preparation of 1,2,3-triazole-isoxazole bisfunctional derivatives and their application in peptidomimetic synthesis
A novel kind of bisfunctional nitrogen heterocycle containing both 1,2,3-triazole and isoxazole scaffolds has been prepared. The protocol utilized alkynyl substituted amines as the bifunctional linkers to combine a copper-free triazole synthesis with a hypervalent iodine-mediated isoxazole cycloaddition through a chemoselective process. This method has also been exemplified in the construction of bis-functional-modified peptidomimetics by combining three reactions in a sequential procedure. This straightforward metal free process may find biological applications. In addition, all of the compounds were analysed by Lapinski’s rule-of-five which is expected to help drug discovery.
Electric Literature of 622-40-2, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 622-40-2 is helpful to your research.
Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem